|
|
Director,
Nano and Pico Characterization Lab
| |
Lab Director,
Gimzewski Lab
| |
Professor,
Chemistry and Biochemistry,
Physical Chemistry
| |
Member,
NanoBiotechnology and Biomaterials,
NanoElectronics, Photonics, Architectonics,
NanoMechanical and Nanofluidic Systems,
California NanoSystems Institute,
Institute for Cell Mimetic Space Exploration (CMISE)
| |
Researcher,
Biophysics and Structural Biology,
Physical
|
Education: |
|
Degrees:
|
|---|
Ph.D., (hc) University of the Mediterranean, Aix-Marseille II, France, 2008 -
Ph.D., University of Strathclyde, Glasgow, Scotland, 1977
B.S., University of Strathclyde, Glasgow, Scotland, 1974
|
|
Certifications: |
|
Professional Societies:
|
|---|
2009 Royal Society, Elected Fellow
2004 International Society for Nanoscale Science, Computation and Engineering, Elected Member
2002 World Innovation Foundation , Elected Fellow
2001 Royal Academy of Engineering, London, United Kingdom (FREng), Elected Fellow
1995 Institute of Physics (FinstP), London, UK, Elected Fellow
|
|
|
|
Contact Information:
| Laboratory Address: |
Young Hall B064
|
|---|
| Work Address: |
Young Hall 3042A
|
|---|
|
Lab Number:
|
1 (310) 206-8259
Lab
|
|---|
|
Work Phone Number:
|
1 (310) 794-7514
Office
|
|---|
|
Research Interests:
|
My interests are in the area of science and technology at the ultimate limits of fabrication, measurement and function. This fascination started when I joined IBM in 1983 when I was fortunate enough to learn a new way to see atoms and molecules. This ability to see or touch atoms and molecules is one of the inspirational forces behind potentially revolutionary technologies we will see in our lifetimes and we are just starting to make what were dreams realities of the future. This will require a whole new generation of scientists and engineers and that is why I am pleased to be at UCLA.
My current interests fall into three areas of research:
- Architectonics of three dimensional nanostrutures and nanosystems. Specifically, we recently made a unique breakthrough in the fabrication of the first single crystals of single walled carbon nanotubes (SWCNT's). All of the tubes are identical and metallic. They are the strongest material mankind has ever made. If we cancontrol the production methods of these tubes we could make the concept of a space elevator, as proposed by the science fiction writer Arthur C. Clarke, a reality. There are numerous applications for this new material especially in the area of energy.
- Biomolecular nanomechanical systems. The electronics industry has invested vast sums of money into research in the area of silicon, microfabrication, and micromachining. However, only a small percentage of this research work and fabrication methodology finds itself into microelectronic products such as integrated circuits. On the other hand, biotechnology and pharmaceutical industries, while very advanced on the chemical side, is only beginning to realize possibilities of miniaturization of sensing arrays, diagnostic methods, and even more futuristically, smart drug delivery systems. My research is aimed at using much of the untapped silicon micromachining and fabrication technologies for bio-sensing and actuation applications using nanomechanics.
- Chemistry, physics, and mechanics of single molecules. This research is aimed at exploring the inter-relationship of quantum mechanics, chemical design and synthesis, and molecular mechanics at the level of individual molecules. Research is highly interdisciplinary combining the skills of synthetic chemists, theorists, and nanoscale scientists, particularly in the area of imaging and spectroscopy. The research is quite fundamental and has a clear long-range goal: programmed functionality of a single molecule. Possible areas of future application include quantum computing, molecular machines, and high-density peta-bit memories. A theoretical goal also includes the operation of a machine that would approach an energy-efficiency close to the limit set by the second law of thermodynamics.
|
Technical Research Interest:
Professor Gimzewski's Pico Lab at UCLA is concerned
with developing a nanosystems approach to interesting areas of research
connected to radical shifts in technology. The projects themselves stem
form the ability to image and manipulate matter all the way up from the
atomic scale. Pico Lab is equipped with state of the art techniques that
enable atoms and molecules to be studies and manipulated in environments
that vary for extreme vacuum at cryogenic temperatures. Nanomechanics is
a new area of science that has evolved in the last ten years or so. It is
concerned with the mechanics of systems with components or motions on
the scale of the nanometer. It turns out that mechanical processes
appear in most living systems and much of the research work has expended
from molecular systems to cell based or whole animal investigations.
These latest studies are specifically aimed at medical diagnostics, stem
cell research and biosensor related applications. Biological systems
also form the focus of bio-inspired materials and devices in which
cellular systems are being used as models for the design of new
paradigms in engineering.
Gimzewski embraces the convergence of all disciplines to
develop a new form of thinking necessary for Nanotechnology
to have a global societal and economic benefit within the next
10 years. This convergence goes beyond Science, Medicine and
Engineering, and embraces the Arts as an essential part of the
process.
|
Additional Information:
Dr. Gimzewski is a Distinguished Professor of Chemistry at the University of California, Los Angeles and Director of the Nano & Pico Characterization Core Facility of the California NanoSystems Institute. Prior to joining the UCLA faculty, he was a group leader at IBM Zurich Research Laboratory, where he research in nanoscale science and technology for more than 18 years. Dr. Gimzewski pioneered research on mechanical and electrical contacts with single atoms and molecules using scanning tunneling microscopy (STM) and was one of the first persons to image molecules with STM. His accomplishments include the first STM-based fabrication of molecular suprastructures at room temperature using mechanical forces to push molecules across surfaces, the discovery of single molecule rotors and the development of new micromechanical sensors based on nanotechnology, which explore ultimate limits of sensitivity and measurement. This approach was recently used to convert biochemical recognition into Nanomechanics. His current interests are in the nanomechanics of cells and bacteria where he collaborates with the UCLA Medical and Dental Schools. He is involved in projects that range from the operation of X-rays, ions and nuclear fusion using pyroelectric crystals, direct deposition of carbonn nanotubes and single molecule DNA profiling. Dr. Gimzewski is also involved in numerous art-science collaborative projects that have been exhibited in museums throughout the world.
|
|
Petrou I, Heu R, Stranick M, Lavender S, Zaidel L, Cummins D, Sullivan RJ, Hsueh C, Gimzewski JK, A breakthrough therapy for dentin hypersensitivity: how dental products containing 8% arginine and calcium carbonate work to deliver effective relief of sensitive teeth, J. Clin. Dent., 2009, 20 (1), 23-31.
Cross SE, Jin Y-S, Rao J, Gimzewski JK, Applicability of AFM in cancer detection, Nat. Nanotech., 2009, 4, 72-73.
Reed J, Schmit J, Han S, Wilkinson P, Gimzewski JK, Interferometric profiling of microcantilevers in liquid, Optics and Lasers in Eng., 2009, 47, 217-222.
Reed J, Ramakrishnan S, Schmit J, Gimzewski JK, Mechanical Interferometry of Nanoscale Motion and Local Mechanical Properties of Living Zebrafish Embryos, ACS Nano (Online), 2009.
Stieg AZ, Rasool HI, Gimzewski JK, A flexible, highly stable electrochemical scanning probe microscope for nanoscale studies at the solid-liquid interface, Rev. Scientific Inst., 2008, 79, 103701.
Cross SE, Jin Y-S, Tondre J, Wong R, Rao J, Gimzewski JK, AFM-based analysis of human metastatic cancer cells, Nanotech., 2008, 19 (38).
Reed J, Walczak W, Petzold O, Gimzewski JK, In Situ Mechanical Interferometry of Matrigel Films, Langmuir, 2008, 25 (1), 36-39.
Reed J, Troke J, Schmit J, Han S, Teitell M, Gimzewski JK, Live Cell Interferometry Reveals Cellular Dynamism During Force Propagation, ACS Nano, 2008, 2 (5), 841-846.
Wilkinson PR, Klug WS, Van Leer B, Gimzewski JK, Nanomechanical properties of piezoresistive cantilevers: theory and experiment, J. Appl. Phys., 2008, 104 (10).
|
|
