California NanoSystems Institute
CNSI
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Benjamin Wu, D.D.S., Ph.D.

   
Co-Director, Weintraub Center for Reconstructive Biotechnology
Associate Professor, Bioengineering
Member, Neuroengineering Training Program, NanoBiotechnology and Biomaterials, Brain Research Institute, California NanoSystems Institute, UCLA Cardiovascular Stem Cell Research Center

Education:
Degrees:
Ph.D., Massachusetts Institute of Technology, Department of Materials Science and Engineering, 1998
D.D.S.:
1987 University of the Pacific, School of Dentistry, San Francisco, California, University of the Pacific, School of Dentistry, San Francisco, California

Certifications:
Professional Societies:
Academy of Prosthodontics, Member

Education:
Medical Experience:
1995 Department of Restorative Dentistry, Harvard School of Dental Medicine, Specialty Certificate in Prosthodontics

Contact Information:
Email Address: benwu@ucla.edu
Mailing Address: UCLA
Department of Bioengineering
5121 K Engineering V
Box 951595
Los Angeles, CA 90095
UNITED STATES
Home Page: http://www.bioeng.ucla.edu/facultyresearch/facultyprofiles/wu.html
Work Phone Number: 310-794-7094 Office
Technical Research Interest:

My research aims to regenerate lost tissues based on the following biomimetic strategy: (i) learn from natural developmental biology, wound healing, and tissue remodeling; (ii) copy nature and engineer biomimetic microenvironments to promote tissue repair; and (iii) investigate the mechanisms by which progenitor cells and biomolecules interact with engineered microenvironments, which are created by controlling surface bound and/or diffusible biochemical signals and/or biomechanical signals.


Additional Information:

Prof. Ben Wu received his D.D.S. from the University of Pacific, his advanced prosthodontics specialty certificate at the Harvard School of Dental Medicine, and his Ph.D. in Materials Science and Engineering from the Massachusetts Institute of Technology. He is currently Associated Professor and Vice Chair of the UCLA Department of Bioengineering, with joint appointment in the Department of Materials Science and Engineering, and in the School of Dentistry at UCLA. Prof. Wu is Co-Director of the Weintraub Center for Reconstructive Biotechnology, and a member of the UCLA Brain Research Institute, the California NanoSystems Institute, and the Academy of Prosthodontics.

Selected Publications:

De Ugarte DA. Choi E. Weitzbuch H. Wulur I. Caulkins C. Wu BM. Fonkalsrud EW. Atkinson JB. Dunn JCY, Mucosal Regeneration of a Duodenal Defect Using SIS, The American Surgeon, 2004, 70, 49-51.
Yuki I. Uchiyama N. Nien YL. Lee D. Murayama Y. Ebara M. Ishii A. Chiang A. Vinters HV. Nishimura I. Wu BM. Vinuela F., In Vitro and In Vivo Evaluations of Bioabsorbable Polymeric Materials for Possible Use as Embolic Materials in Cerebral Aneurysms., Neurosurgery, Accepted.
Choi, C. H. Heydarkhan-Hagvall, S. Wu, B. M. Dunn, J. C. Y. Beygui, R. E. Kim, C. J. , Cell growth as a sheet on three-dimensional sharp-tip nanostructures, Journal of Biomedical Materials Research Part A, 2009, 89A (3), 804-817.
Lee, M. Wu, B. M. Dunn, J. C. Y. , Effect of scaffold architecture and pore size on smooth muscle cell growth, Journal of Biomedical Materials Research Part A, 2008, 87A (4), 1010-1016.
Brown, D. A. MacLellan, W. R. Dunn, J. C. Y. Wu, B. M. Beygui, R. E. , Hypoxic cell death is reduced by pH buffering in a model of engineered heart tissue, Artificial Cells Blood Substitutes and Biotechnology, 2008, 36 (2), 94-113.
Lee, M. Wu, B. M. Stelzner, M. Reichardt, H. M. Dunn, J. C. Y. , Intestinal smooth muscle cell maintenance by basic fibroblast growth factor, Tissue Engineering Part A, 2008, 14 (8), 1395-1402.
Chow, M. Duong, H. Wu, B. Tawil, B. , Mesenchymal stem cells differentiation into osteoblasts on 2D and in 3D fibrin scaffolds, Wound Repair and Regeneration, 2008, 16 (2), 175.
Kramerova, I. Kudryashova, E. Wu, B. Ottenheijm, C. Granzier, H. Spencer, M. J. , Novel role of calpain-3 in the triad-associated protein complex regulating calcium release in skeletal muscle, Human Molecular Genetics, 2008, 17 (21), 3271-3280.
Dave, D. S. Gunther-Lopez, V. Zhang, R. Leung, J. Kun, S. Gollapudi, K. Wu, B. Rodriguez, L. V. , Periurethral injection of autologous adipose-derived stem cells with hepatocyte growth factor-impregnated PLGA microspheres for treatment of stress urinary incontinence in an animal model, Journal of Urology, 2008, 179 (4), 109-109.
Heydarkhan-Hagvall, S. Schenke-Layland, K. Dhanasopon, A. P. Rofail, F. Smith, H. Wu, B. M. Shemin, R. Beygui, R. E. MacLellan, W. R. , Three-dimensional electrospun ECM-based hybrid scaffolds for cardiovascular tissue engineering, Biomaterials, 2008, 29 (19), 2907-2914.
Brown DA, MacLellan WR, Laks H, Dunn JC, Wu BM, Beygui RE, Analysis of oxygen transport in a diffusion-limited model of engineered heart tissue, Biotechnol Bioeng, 2007, 97 (4), 962-75.
Brown DA, MacLellan WR, Wu BM, Beygui RE, Analysis of pH gradients resulting from mass transport limitations in engineered heart tissue, Annals of Biomed Eng., 2007, 35 (11), 1885-1897.
Choi CH. Hagwall SH. Wu BM. Dunn JCY. Kim CJ, Cell interactions with 3D sharp tip nanotopography, Biomaterials, 2007, 28 (9), 1672-9.
Lee M. Wu BM. Dunn JYC, Effect of scaffold architecture and pore size on smooth muscle cell growth, J. Biomed. Mat Res. Part A, 2007, Accepted for Publication - In Press.
Hagerman E. Shim J. Gupta V. Wu BM, Evaluation of laser spallation as a technique for measurement of cell adhesion strength, J. Biomed. Mat. Res. Part A 82A, 2007, 45, 852-860.
Brown DA, MacLellan WR, Wu BM, Beygui RE, Hypoxic cell death is reduced by pH buffering in a model of engineered heart tissue, Artificial Cells, Blood Substitutes & Biotechnology, 2007, In Press.
Mack JJ, Cox BN, Lee M, Dunn JYC, Wu BM, Magnetically Actuable Polymer Nanocomposites for Bioengineering Applications., J. Mater. Sci., 2007, 42 (15), 6139-6147.
Cowan CM, Aghaloo T, Chou YF, Walder B, Zhang X, Soo C, Ting K, Wu BM., MicroCT Evaluation of Three-Dimensional Mineralization in Response to BMP-2 Doses In Vitro and in Critical Sized Rat Calvarial Defects, Tissue Engineering, 2007, 13 (3), 501-512.
Lee M. Iruela Arispe ML. Wu BM. Dunn JCY, Modulation of protein delivery from modular polymer scaffolds, Biomaterials, 2007, 28 (10), 1862-70.
Wan DC, Pomerantz JH, Brunet LJ, Kim JB, Chou YF, Wu, BM, Harland R, Blau HM, Longaker MT, Noggin suppression enhances in vitro osteogenesis and accelerates in vivo bone formation, J. Biol Chem, 2007, 282 (36), 26450-26459.
Aghaloo T, Amantea CM. Cowan KM, Richardson JA, Wu B, Parhami F, Tetradis S, Oxysterols enhance osteoblast differentiation in vitro and bone healing in vivo, J. Orthop Res., 2007, 25 (11), 1488-1497.
Wan DC, Siedhoff MT, Kwan MD, Nacamuli RP, Wu BM, Longaker MT, Refining Retinoic Acid Stimulation for Osteogenic Differentiation of Murine Adipose-Derived Adult Stromal Cells, Tissue Engineering, 2007, 13 (7), 1623-1631.
Cowan CM, Jiang X, Hsu T, Soo C, Zhang J, Wang J, Kuroda S, Wu B, Zhang Z, Zhang X, Ting K, Synergistic effects of Nell-1 and BMP-2 on the osteogenic differentiation of myoblasts, J Bone Mineral Res, 2007, 22 (6), 918-30.
Lu SS, Zhang X, Soo C, Hsu T, Napoli A, Aghaloo T, Wu BM, Tsou P, Ting K, Wang JC, The osteoinductive properties of Nell-1 in rat spinal fusion model, The Spine Journal, 2007, 7 (1), 50-60.
Lee D, Yuki I, Murayama Y, Chiang A, Nishimura I, Vinters HV, Wang CJ, Nien YL, Ishii A, Wu BM, Vinuela F, Thrombus organization and healing in the swine experimental aneurysm model. Part I. A histological and molecular analysis, J. Neurosurgery, 2007, 107 (1), 94-108.
Cowan, C. M. Jiang, X. Q. Hsu, T. Soo, C. Zhang, B. J. Wang, J. Z. Kuroda, S. Wu, B. Zhang, Z. Y. Zhang, X. L. Ting, K. , Synergistic effects of Nell-1 and BMP-2 on the osteogenic differentiation of myoblasts, Journal of Bone and Mineral Research, 2007, 22 (6), 918-930.
Petrigliano FA, English C. Barba D. Esmende S. Wu BM. McAllister MD, The Effects of Local bFGF Release and Uniaxial Strain on Cellular Adaptation and Gene Expression in a 3D Environment: Implications for Ligament Tissue Engineering, Tissue Engineering, 2007, 13 (11), 1-11.
Yuki I, Lee D, Murayama Y, Chiang A, Vinters HV, Nishimura I, Wang CJ, Ishii A, Wu BM, Vinuela V, Thrombus organization and healing in an experimental aneurysm model. Part II. The effect of various types of bioabsorbable polymeric coils, J. Neurosurgery, 2007, 107 (1), 109-120.
Lee, M. Chen, T. T. Iruela-Arispe, M. L. Wu, B. M. Dunn, J. C. Y. , Modulation of protein delivery from modular polymer scaffolds, Biomaterials, 2007, 28 (10), 1862-1870.
Cowan, C. M. Cheng, S. Ting, K. Soo, C. Walder, B. Wu, B. Kuroda, S. Zhang, X. L. , Nell-1 induced bone formation within the distracted intermaxillary suture, Bone, 2006, 38 (1), 48-58.
Ho, W. Tawil, B. Dunn, J. C. Y. Wu, B. M. , The behavior of human mesenchymal stem cells in 3D fibrin clots: Dependence on fibrinogen concentration and clot structure, Tissue Engineering, 2006, 12 (6), 1587-1595.
Dunn JCY. Chan WY, Cristini V. Kim JS. Lowengrub J. Singha S. Wu BM, Analysis of Cell Growth in Three-Dimensional Scaffolds, Tissue Engineering, 2006, 12, 705-716.
Wu, B. Kitagawa, K. Liu, B. Zhang, N. Y. Xiong, Z. M. Inagaki, C. , Attenuation of amyloid beta (Abeta)-induced inhibition of phosphatidylinositol 4-kinase activity by Abeta fragments, Abeta20-29 and Abeta31-35, Neurosci Lett, 2006, 396 (2), 148-52.
Wu, B. K. Li, C. C. Chen, H. J. Chang, J. L. Jeng, K. S. Chou, C. K. Hsu, M. T. Tsai, T. F. , Blocking of G1/S transition and cell death in the regenerating liver of Hepatitis B virus X protein transgenic mice, Biochem Biophys Res Commun, 2006, 340 (3), 916-28.
Rodriguez LV. Alfonso Z. Zhang R. Leung J. Wu BM. Ignarro LJ. , Clonogenic multipotent stem cells in human adipose tissue differentiate into functional smooth muscle cells, PNAS, 2006, 103 (32), 12167-12172.
Wu, B. Liu, J. , Commutability between the semiclassical and adiabatic limits, Phys Rev Lett, 2006, 96 (2), 020405.
Mendoza J., Chang C., Blalock CL., Atkinson JB., WU BM., Dunn JYC., Contractile Function of the Mechanically Lengthened Intestine, J. Surgical Research, 2006, 136 (1), 8-12.
Wu, B. , Differential gene expression detection and sample classification using penalized linear regression models, Bioinformatics, 2006, 22 (4), 472-6.
Puapong DP., Wu BM., Lam MM., Atkinson JB., Dunn JCY., Distension enterogenesis: Increasing the Size and Function of Small Intestine, J. Pediatric Surgery , 2006, 41, 763-7.
Catelas I. Sese N. Dunn JCY. Helgerson S. Tawil B. Wu BM, Human Mesenchymal Stem Cells Proliferation and Osteogenic Differentiation in Fibrin Gels in vitro, Tissue Engineering, 2006, 12 (8), 1-12.
Hagerman EM. Chao SHH. Dunn JCY. Wu BM, Initial Adhesion Events for IEC-6: signal transduction, cell spreading, and cell adhesion strength, Journal of Biomedical Materials Research , 2006, 76 (2), 272-278.
Aghaloo T, Cowan K, Chou YF, Zhang X, Lee HF, Miao S, Hong N, Kuroda S, Wu B, Ting K, Soo C, Nell-1 Induced Bone Regeneration in Calvarial Defects, Am J Pathol., 2006, 169 (3), 903-15.
Cowan, C. M. Cheng, S. Ting, K. Soo, C. Walder, B. Wu, B. Kuroda, S. Zhang, X. , Nell-1 induced bone formation within the distracted intermaxillary suture, Bone, 2006, 38 (1), 48-58.
Zhang X, Cowan K, Jiang X, Soo C, Miao S, Carpenter D, Wu, B, Kuroda K, and Ting K., Nell-1 induces acrania-like cranioskeletal deformities during mouse embryonic development., Lab Invest., 2006, 86 (7), 633-44.
Kramerova, I. Kudryashova, E. Wu, B. Spencer, M. J. , Regulation of the M-cadherin-beta-catenin complex by calpain 3 during terminal stages of myogenic differentiation, Molecular and Cellular Biology, 2006, 26 (22), 8437-8447.
Chu Y. Wu BM. McCabe ER. Dunn JCY, Serum Free cultures of murine adrenal cortical cells. , J. Pediatric Surgery, 2006, 41, 2008-2012.
Chang P.C.Y. Mendoza J. Park J. Lam MM. Wu BM. Atkinson JB. Dunn JCY., Sustainability of mechanically lengthened bowel in rats., J. Pediactric Surgery, 2006, 4, 2019-2022.
Ho W. Tawil B. Dunn JCY. Wu BM, The Behavior of Human Mesenchymal Stem Cells In 3D Fibrin Clots: Dependence on Fibrinogen Concentration and Clot Structure, Tissue Engineering, 2006, 12 (6), 1-9.
Dunn, JCY. Wu, BM, Tissue Engineering of Intestine, Encyclopedia of Biomaterials and Biomedical Engineering, 2006, 1-7.
Petrigliano FA., McAllister MD., Wu BM., Tissue Engineering of the ACL: A Review of Current Strategies, Arthroscopy, 2006, 22 (4), 441-451.
Chou, Y.F., Wulur, I., Dunn, JCY., Wu, BM., Biomimetic Nano-Ordered Apatites , Handbook of Nanostructured Biomaterials and Their Applications. edited by H. S. Nalwa,, 2005, 2 (6), 198-222.
Cowan, C. M. Aalami, O. O. Shi, Y. Y. Chou, Y. F. Mari, C. Thomas, R. Quarto, N. Nacamuli, R. P. Contag, C. H. Wu, B. Longaker, M. T. , Bone morphogenetic protein 2 and retinoic acid accelerate in vivo bone formation, osteoclast recruitment, and bone turnover, Tissue Eng, 2005, 11 (3-4), 645-58.
Wu, B. Sun, Y. H. Wang, Y. W. Wang, Y. P. Zhu, Z. Y. , Characterization of transgene integration pattern in F4 hGH-transgenic common carp (Cyprinus carpio L.), Cell Res, 2005, 15 (6), 447-54.
Yang CY. Brooks E. Li Y. Wong DTW. Denny P. Ho CM. Qi F. Shi W. Wolinsky L. Wu BM. Montemagno CD., Detection of Picomolar levels of interleukin-8 in human saliva by SPR, Lab on a Chip, 2005, 5 (10), 1017-1023.
Wu, B. Gao, J. Wang, M. W. , Development of a complex scintillation proximity assay for high-throughput screening of PPARgamma modulators, Acta Pharmacol Sin, 2005, 26 (3), 339-44.
Wu, B. Yuan, D. Lou, B. Han, L. Liu, C. Zhang, C. Hong, M. , Dynamic formation of coordination polymers versus tetragonal prisms and unexpected magnetic superexchange coupling mediated by encapsulated anions in the cobalt(II) 1,3-bis(pyrid-4-ylthio)propan-2-one series, Inorg Chem, 2005, 44 (25), 9175-84.
Park J. Puapong DP. Wu BM. Atkinson JB. Dunn JCY, Enterogenesis by Mechanical Lengthening: Morphology and Function of the Lengthened Small Intestine, J. Pediatric Surg, 2005, 29 (12), 1823-1827.
Cowan, CM Soo, C Ting, K Wu, B, Evolving concepts in bone tissue engineering, Current topics in developmental biology, 2005, 66 (86), 239-85.
Brown, D. A. Chou, Y. F. Beygui, R. E. Dunn, J. C. Wu, B. M. , Gelatin-embedded cell-polymer constructs for histological cryosectioning, J Biomed Mater Res B Appl Biomater, 2005, 72 (1), 79-85.
Wu, B. Nara, K. Hogetsu, T. , Genetic structure of Cenococcum geophilum populations in primary successional volcanic deserts on Mount Fuji as revealed by microsatellite markers, New Phytol, 2005, 165 (1), 285-93.
Chou YF. Dunn JCY. Wu BM, In vitro response of MC3T3-E1 preosteoblasts within three-dimensional apatite-coated PLGA scaffolds, Journal of Biomedical Materials Research , 2005, 75b, 81-90.
Wu, B. N. Tu, H. F. Welsh, D. G. Chen, I. J. , KMUP-1 activates BKCa channels in basilar artery myocytes via cyclic nucleotide-dependent protein kinases, Br J Pharmacol, 2005, 146 (6), 862-71.
Wu, B. Zhang, G. Zhang, Y. Shuang, S. Choi, M. M. , Measurement of glucose concentrations in human plasma using a glucose biosensor, Anal Biochem, 2005, 340 (1), 181-3.
Brown, D. A. Beygui, R. E. MacLellan, W. R. Laks, H. Dunn, J. C. Wu, B. M. , Modulation of gene expression in neonatal rat cardiomyocytes by surface modification of polylactide-co-glycolide substrates, J Biomed Mater Res A, 2005, 74 (3), 419-29.
Brown DA. Beygui RE. Antrobus S. Ross RS. MacLellan WR. Laks H. Dunn JYC. Wu BM. , Modulation of hypertrophy in neonatal rat cardiomyocytes by surface modification of synthetic substrates, J. Biomedical Materials Research, 2005, 74A (3), 419-429.
Wu, B. Wong, D. Lu, S. Dickstein, S. Silva, M. Gelety, T. J. , Optimal use of fresh and frozen-thawed testicular sperm for intracytoplasmic sperm injection in azoospermic patients, J Assist Reprod Genet, 2005, 22 (11-12), 389-94.
Jarrahy R., Huang W., Rudkin GH., Lee JM., Ishida K., Berry MD., Sukkarieh M., Wu BM., Yamaguchi DT., Miller TA., Osteogenic differentiation is inhibited and angiogenic expression is enhanced in MC3T3-E1 cells cultured on three-dimensional scaffolds, Am J Physiology - Cell Physiology, 2005, 289, 408-414.
Wu, B. Elmariah, S. Kaplan, F. S. Cheng, G. Mohler, E. R., 3rd , Paradoxical effects of statins on aortic valve myofibroblasts and osteoblasts: implications for end-stage valvular heart disease, Arterioscler Thromb Vasc Biol, 2005, 25 (3), 592-7.
Wu, B. Klatzky, R. L. Shelton, D. Stetten, G. D. , Psychophysical evaluation of in-situ ultrasound visualization, IEEE Trans Vis Comput Graph, 2005, 11 (6), 684-93.
Lee M. Dunn JCY. Wu BM., Scaffold Fabrication by Indirect 3D Printing, Biomaterials, 2005, 26 (20), 4281-4289.
Wu, B. Y. Gao, L. H. Duan, Z. M. Wang, K. Z. , Syntheses and DNA-binding studies of two ruthenium(II) complexes containing one ancillary ligand of bpy or phen: [Ru(bpy)(pp[2,3]p)2](ClO4)2 and [Ru(phen)(pp[2,3]p)2](ClO4)2, J Inorg Biochem, 2005, 99 (8), 1685-91.
Chang, T. H. Wu, B. R. Chiang, M. Y. Liao, S. C. Ong, C. W. Hsu, H. F. Lin, S. Y. , Synthesis and mesomorphic behavior of a donor-acceptor-type hexaazatriphenylene, Org Lett, 2005, 7 (19), 4075-8.
Puk CK., Gamradt S., Wu B.M., McAllister D, The Effects of Short-Term Stimulation on Fibroblast Spreading in an Invitro 3D Syste, J. Biomedical Materials Research , 2005, 76A (4), 665-673.
Li Y, Denny P, Ho CM, Montemagno C, Shi W, Qi F, Wu B, Wolinsky L, Wong DT., The Oral Fluid MEMS/ NEMS Chip (OFMNC): diagnostic and translational applications, Advanced Dental Resesarch, 2005, 18 (1), 3-5.
Wu, B. T. Hung, P. F. Chen, H. C. Huang, R. N. Chang, H. H. Kao, Y. H. , The apoptotic effect of green tea (-)-epigallocatechin gallate on 3T3-L1 preadipocytes depends on the Cdk2 pathway, J Agric Food Chem, 2005, 53 (14), 5695-701.
Brown DA. Chou YF. Lam M. Beygui RE. Dunn JYC. Wu BM, Gelatin embedding cell-polymer constructs for frozen sections, J. Biomedical Materials Research, 2005, 72B, 79-85.
Lee, M Dunn, JC Wu, BM, Scaffold fabrication by indirect three-dimensional printing., Biomaterials. , 2005, 26 (20), 4281-9.
Chou, Y. F. Huang, W. Dunn, J. C. Miller, T. A. Wu, B. M. , The effect of biomimetic apatite structure on osteoblast viability, proliferation, and gene expression, Biomaterials, 2005, 26 (3), 285-95.
Wu, B. Muller, J. D. , Time-integrated fluorescence cumulant analysis in fluorescence fluctuation spectroscopy, Biophys J, 2005, 89 (4), 2721-35.
Wu, B. Li, P. Liu, Y. Lou, Z. Ding, Y. Shu, C. Ye, S. Bartlam, M. Shen, B. Rao, Z. , 3D structure of human FK506-binding protein 52: implications for the assembly of the glucocorticoid receptor/Hsp90/immunophilin heterocomplex, Proc Natl Acad Sci U S A, 2004, 101 (22), 8348-53.
Wu, B. T. Su, Y. H. Tsai, M. T. Wasserman, S. M. Topper, J. N. Yang, R. B. , A novel secreted, cell-surface glycoprotein containing multiple epidermal growth factor-like repeats and one CUB domain is highly expressed in primary osteoblasts and bones, J Biol Chem, 2004, 279 (36), 37485-90.
Cowan, CM., Shi S., Alami, OO., Chou, YF., Thomas R. Marie C., Quarto N., Wu BM. Longaker MT. , Adipose-derived Mesenchymal Stromal Cells Tissue Engineer Bone in Critical Sized Mouse Calvarial Defects, Nature Biotechnology, 2004, 22 (5), 560-567.
Dunn, J. C. Chu, Y. Lam, M. M. Wu, B. M. Atkinson, J. B. McCabe, E. R. , Adrenal cortical cell transplantation, J Pediatr Surg, 2004, 39 (12), 1856-8.
Huang W. Carlsen B. Wulur I. Rudkin G. Ishida K. Wu BM. Yamaguchi DT. Miller TA, BMP-2 exerts differential effects on differentiation of rabbit bone marrow stromal cells cultured in two-dimensional and three dimensional systems and is required for in vitro formation in a PLGA scaffold, Exper. Cell Research, 2004, 299 (2), 325-34.
St. John M. Li Y. Zhou XF. DennyD. Ho CM. Montemagno C. Shi WY. Qi FX. Wu BM. Sinha U. Jordan R. Wolinsky L. Park NH. Abemayor E. Wong DTW, IL-6 and IL-8: Potential Biomarkers for Oral Cavity and Oropharyngeal SSC, Arch of Otolaryngology/Head & Neck Surgery , 2004, 130 (8), 929-35.
Wu, B. N. Lin, R. J. Lo, Y. C. Shen, K. P. Wang, C. C. Lin, Y. T. Chen, I. J. , KMUP-1, a xanthine derivative, induces relaxation of guinea-pig isolated trachea: the role of the epithelium, cyclic nucleotides and K+ channels, Br J Pharmacol, 2004, 142 (7), 1105-14.
Fang, C. Wu, B. Zhou, X. , Nafion membrane electrophoresis with direct and simplified end-column pulse electrochemical detection of amino acids, Electrophoresis, 2004, 25 (2), 375-80.
Deng, Y. M. Wu, B. J. Witting, P. K. Stocker, R. , Probucol protects against smooth muscle cell proliferation by upregulating heme oxygenase-1, Circulation, 2004, 110 (13), 1855-60.
Kreth, J., Hagerman, E., Tam, K., Merritt, J., Wu, B.M., Myung, M., Shi, W., and Qi, F, Quantitative Analyses of Streptococcus mutans Biofilms with Quartz Crystal Microbalance, Microjet Impingement, and Confocal Microscopy, Biofilms, 2004, 1 (4), 277-284.
Chen, X. Grzegorczyk, T. M. Wu, B. I. Pacheco, J., Jr. Kong, J. A. , Robust method to retrieve the constitutive effective parameters of metamaterials, Phys Rev E Stat Nonlin Soft Matter Phys, 2004, 70 (1 Pt 2), 016608.
Liu, B. Hattori, N. Jiang, B. Nakayama, Y. Zhang, N. Y. Wu, B. Kitagawa, K. Taketo, M. Matsuda, H. Inagaki, C. , Single cell RT-PCR demonstrates differential expression of GABAC receptor rho subunits in rat hippocampal pyramidal and granule cells, Brain Res Mol Brain Res, 2004, 123 (1-2), 1-6.
Yang, W. Wu, B. Asakura, S. Kohno, I. Matsuda, M. , Soluble fibrin augments spreading of fibroblasts by providing RGD sequences of fibrinogen in soluble fibrin, Thromb Res, 2004, 114 (4), 293-300.
Wu, B. M. Nakamura, M. Rezaee, M. , Stent implantation for coronary aneurysm with edge stenosis: angiographic and intravascular analysis, J Invasive Cardiol, 2004, 16 (3), 149-51.
He, Y. Yang, J. Wu, B. Robinson, D. Sprankle, K. Kung, P. P. Lowery, K. Mohan, V. Hofstadler, S. Swayze, E. E. Griffey, R. , Synthesis and evaluation of novel bacterial rRNA-binding benzimidazoles by mass spectrometry, Bioorg Med Chem Lett, 2004, 14 (3), 695-9.
Wu, B. , Testing three competing hypotheses for explaining lethal violence, Violence Vict, 2004, 19 (4), 399-411.
Chou YF. Chiou WA. Xu Y. Dunn JCY. Wu BM, The Effect of pH on Structural Evolution of Accelerated Biomimetic Apatite Formation, Biomaterials, 2004, 25, 5323-5331.
Wu, B. Liu, Q. Sulikowski, G. A. , Total synthesis of apoptolidinone, Angew Chem Int Ed Engl, 2004, 43 (48), 6673-5.
Qin, W. Tyshenko, M. G. Wu, B. S. Walker, V. K. Robertson, R. M. , Cloning and characterization of a member of the Hsp70 gene family from Locusta migratoria, a highly thermotolerant insect, Cell Stress Chaperones, 2003, 8 (2), 144-52.
Wu, B. Abbott, T. Fishman, D. McMurray, W. Mor, G. Stone, K. Ward, D. Williams, K. Zhao, H. , Comparison of statistical methods for classification of ovarian cancer using mass spectrometry data, Bioinformatics, 2003, 19 (13), 1636-43.
Sukotjo C. Lin A. Song KK. Ogawa I. Wu BM. Nishimura I, Oral fibroblast expression of wound inducible transcript-3.0 (wit-3.0) accelerates collagen gel contraction in vitro, J. Biological Chemistry, 2003, 278 (51), 51527-51534.
Zhang X. Carpenter D. Bokui N. Soo C. MiaoS. Truong T. Wu BM. Chen I. Vastardis H. Tanizawa K. Kuroda S. Ting K., Overexpression of Nell-1, a craniosynostosis associated gene, induces apoptosis in osteoblasts during craniofacial development., Journal of Bone and Mineral Research , 2003, 18, 2126-2134.
Nishimura I. Garrell R. Hedrick M. Iida K. Osher S. Wu BM, Precusor Tissue Engineering Analogues as a Tissue Engineering Strategy, Tissue Engineering, 2003, 9 (1), 77-89.
Hong, B. Wu, B. Li, Y. , Production of C-terminal amidated recombinant salmon calcitonin in Streptomyces lividans, Appl Biochem Biotechnol, 2003, 110 (2), 113-23.
Wu, B. Yee, A. Pineda-Lucena, A. Semesi, A. Ramelot, T. A. Cort, J. R. Jung, J. W. Edwards, A. Lee, W. Kennedy, M. Arrowsmith, C. H. , Solution structure of ribosomal protein S28E from Methanobacterium thermoautotrophicum, Protein Sci, 2003, 12 (12), 2831-7.
Drachman, D. B. Wu, J. M. Miagkov, A. Williams, M. A. Adams, R. N. Wu, B. , Specific immunotherapy of experimental myasthenia by genetically engineered APCs: the "guided missile" strategy, Ann N Y Acad Sci, 2003, 998, 520-32.
Wu, B. Yang, J. Robinson, D. Hofstadler, S. Griffey, R. Swayze, E. E. He, Y. , Synthesis of linked carbohydrates and evaluation of their binding for 16S RNA by mass spectrometry, Bioorg Med Chem Lett, 2003, 13 (22), 3915-8.
Chen, J. Guo, J. Sun, J. Jiang, W. Wu, B. , TCM treatment of Parkinson's syndrome--a report of 40 cases, J Tradit Chin Med, 2003, 23 (3), 168-9.