California NanoSystems Institute
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Course Details

ENV HLT 180/280 - Principles of Nanobiological Interactions & Nanotoxicology
Fall 2008
Subject Area: Environmental Health Sciences
Tuesday / Thursday: 6:00 - 7:50 pm

View 2008 Fall Course Outline

Nanotoxicology capstone course for graduate and undergraduate students from all disciplines; three credit course that meets part of the degree requirements.

Course Objectives
  • Introduce students to commonly used vocabulary in NanoScience that will be required to appreciate the biological interactions and potential toxicity of nanomaterials
  • Discuss synthesis and physical-chemical characterization of engineered nanomaterials
  • Develop an understanding of unique properties of engineered nanomaterials and how these properties contribute to biological interactions
  • Relate properties of engineered nanomaterials to their potential for transport, reactivity,
Course Outline
Lectures Topic
Nanomaterials and Toxicology
1 Lessons for Nanomaterial Safety from Chemical Toxicity
2 Introduction to Nanomaterial Toxicity: Why do we need a Science?
Properties of Nanomaterials
3 Nanoparticle Formation & Manufacture
4 Physical and Chemical Properties of Nanomaterials
5 Midterm Exam
   
Exposure Assessment and Physical-Chemical Characterization
6 Exposure Assessment
7 Methods and Instrumentation for Detection of Nanoparticles
8 Fate and Transport of Nanomaterials in Environmental Media (air, water, soil)
9 Impact of Nanomaterials on Ecosystems and Bacteria
Nanomaterial Applications
10 Nano-Bio Materials & their Applications
11 Nanotechnology and Water Quality
12 Life Cycle Assessment of Nanomaterials
Cellular Toxicity
13 Nanomaterial Uptake in Cells, Subcellular Distribution and Imaging
14 Use of a Mechanism of Cellular Injury (Oxidative Stress) to Build a Predictive Toxicological paradigm for Safety Assessment
15 Nanobiosensors and High Throughput Screening for Toxicological Assessment
16 Forecasting Toxic Risk for the Nano Technology Industry
Risk Assessment, Management and Policy
17 Risk Assessment
18 Risk Management and Public Policy
19 Nanoparticles and Cancer
20 Review
Exam Week: Final Exam