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The Nanotoxicology Research & Training Program is an interdisciplinary program that has been offered under the umbrella of the CNSI since
Spring 2007. Drawing from the expertise of 20 faculty, 8 departments, and four schools, this program aims to train a new generation of students to understand
nanomaterials, their potential toxicity, and risk assessment. The goal of the CNSI education program is to nurture a future workforce of scientists
and engineers with experience using nanoscience and nanoengineering to solve problems in biological and environmental engineering and providing courses on
nanotoxicology will ensure that the next generation of scientists and engineers will be well prepared to meet the health assessment demands of a rapidly evolving
world of nanomaterials development. While there are a few existing courses available at UCLA which focus on toxicology, the Nanotoxicology Research
and Training Program seeks to integrate nanoscience into a broader research community and thereby meet the needs of the rapidly evolving area of nanoscience
R&D. This research and training program will better prepare scientists to evaluate the social and economic impacts of nanomaterials.
Executive Committee, External Advisory Committee, and Faculty
Focus of the Program
The new discipline of Nanotoxicology is currently being built to ensure safe development of nanotechnology and develop
guidelines for testing of all nano scale materials where human and ecosystem health can be affected. There are two components to the NRTP:
Research The involvement of students in discovery-based scientific inquiry is the primary objective of the Nanotoxicology Research and Training
Program. The program aims to develop graduate and undergraduate level course work and research programs for students from various interdisciplinary departments
at UCLA. Six to eight graduate students will be funded each year to participate in the training program.
Research Themes
Training The nanotoxicology capstone course is an interdisciplinary course taught by faculty from the School of Public Health, the David Geffen
School of Medicine, the College of Letters and Sciences, and the Henry Samueli School of Engineering that is open to both graduate and undergraduate students
who are interested in learning about nanotoxicology.
Please click on the link below to see the fall schedule of seminars affiliated with the program.
Fall Schedule
Course Details Nanotoxicology capstone course
Graduate and Undergraduate Students
across all disciplines can participate in this three credit course as part of their degree requirements.
EHS 180/280 – Principles of
Nanobiological Interactions & Nanotoxicology, Fall 2007
Subject Area: Environmental Health Sciences
Tuesday / Thursday: 6:00 – 7:50 pm,
Location tbd
Course Objectives - Introduce students to commonly used vocabulary in NanoScience that will required to appreciate the biological
interactions and potential toxicity of nanomaterials
- Discuss synthesis and physical-chemical characterization of engineered nanomaterials
- Develop an understanding of unique properties of engineered nanomaterials and how these properties contribute to biological interactions
- Relate properties of engineered nanomaterials to their potential for transport, reactivity, uptake, and toxicity in natural environments and in the body
| Course Outline (3 units) |
| Lectures (1.5 hrs) | Topic | Faculty |
| Nanomaterials and Toxicology |
| 1 | Lessons for Nanomaterial Safety from Chemical Toxicity |
Curt Eckhert |
| 2 |
Introduction to Nanomaterial Toxicity: Why do we need a Science? |
Andre Nel | | Properties of Nanomaterials |
| 3 |
Nanoparticle Formation & Manufacture |
Lutz Mädler |
| 4 | Physical and Chemical Properties of Nanomaterials |
Jeff Zink, J. Fraser Stoddart & Bruce Dunn |
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| 5 |
Exam |
6 |
Exposure Assessment |
Nola Janice Kennedy & William Hinds |
| Exposure Assessment and Physical-Chemical Characterization |
| 7 |
Methods and Instrumentation for Detection of Nanoparticles |
Lutz Mädler & Eric M.V. Hoek |
| 8 |
Fate and Transport of Nanomaterials in Environmental Media (air, water, soil) |
Arturo Keller | | 9 |
Impact of Nanomaterials on Ecosystems and Bacteria | Patricia Holden |
| Nanomaterial Applications |
| 10 | Nano-Bio Materials & their Applications |
Heather Maynard, Bruce Dunn & Leonard H. Rome |
| 11 | Nanotechnology and Water Quality | Eric M.V. Hoek |
| 12 |
Life Cycle Assessment of Nanomaterials | Roland Geyer |
| Cellular Toxicity |
| 13 |
Nanomaterial Uptake in Cells, Subcellular Distribution and Imaging |
Leonard H. Rome, Andre Nel & Fuyuhiko Tamanoi |
| 14 |
Use of a Mechanism of Cellular Injury (Oxidative Stress) to Build a Predictive Toxicological paradigm for Safety Assessment |
Andre Nel |
| 15 |
Nanobiosensors and High Throughput Screening for Toxicological Assessment |
Ken Bradley |
| 16 | Forecasting Toxic Risk for the Nano Technology Industry |
Lynne Zucker & Michael Darby | | Exam Week: Final Exam |
| Risk Assessment, Management and Policy |
| 17 | Risk Assessment |
John Froines |
| 18 | Risk Management and Public Policy | John Froines |
| 19 | Nanoparticles and Cancer |
Robert Schiestl, Michael Teitell, W.H. McBride & Oliver Hankinson |
| 20 | Review |
NA |
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To download a PDF of this course outline that includes dates for printing purposes please click
here.
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